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Royals vs. Angels Prediction, Odds, Picks – September 23

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September 23, 2025
Reading Time: 11 mins read
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Blue Jays vs. Royals Highlights | MLB on FOX

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Data Skrive

A pair of hot hitters, Bobby Witt Jr. and Taylor Ward, will be on display when the Kansas City Royals face the Los Angeles Angels on Tuesday at 9:38 p.m. ET, at Angel Stadium. The Royals are favored in this one, at -152, while the underdog Angels have +127 odds to play spoiler. Kansas City (-1.5) is the favorite on the run line. An 8.5-run total has been set for this matchup.

Here’s everything you need to know from a betting perspective on the Royals-Angels game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

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Blue Jays vs. Royals Highlights | MLB on FOX

Check out the best highlights between the Toronto Blue Jays and Kansas City Royals.

Royals vs. Angels Game Information & Odds

  • When: Tuesday, September 23, 2025 at 9:38 p.m. ET
  • Where: Angel Stadium in Anaheim, California
  • How to watch on TV: FDSW and FDSKC
FavoriteFavorite MoneylineUnderdog MoneylineTotalOver Total OddsUnder Total OddsRun LineFavorite Run Line OddsUnderdog Run Line Odds
Royals-152+1278.5-116-104-1.5+109-131

Royals vs. Angels Prediction

  • Score Prediction: Royals 5, Angels 4
  • Total Prediction: Over 8.5 runs
  • Win Probabilities: Royals 50%, Angels 50%

Royals vs. Angels Betting Insights

  • The Royals have won 37, or 57.8%, of the 64 games they’ve played as favorites this season.
  • Kansas City is 13-8 this season when entering a game favored by -152 or more on the moneyline.
  • The Royals have a 60.3% chance to win this game based on the implied probability of the moneyline.
  • The Angels have won in 51, or 43.6%, of the 117 contests they have been named as odds-on underdogs this year.
  • This season, Los Angeles has come away with a win 30 times in 67 chances when named as an underdog of at least +127 or longer on the moneyline.
  • The Angels have an implied victory probability of 44.1% according to the moneyline set for this matchup.

Royals Recent Betting Performance

  • The Royals have been named the moneyline favorite by bookmakers just one time over the last 10 games, and won that matchup.
  • In their last 10 outings (all had set totals), the Royals combined with their opponents to hit the over on the run total seven times.
  • The Royals’ ATS record is 5-5-0 over their past 10 games.

Royals Recent Stats

StatAvg/Total
Record4-6
Runs Per Game5.9
HR15
ERA5.17
K/96.4

Royals Player Insights

  • Witt leads the Royals with a .292 batting average.
  • In all of the majors, Witt ranks 56th in homers and 38th in RBI.
  • Witt has collected a hit in three straight games. During his last five outings he is batting .304 with two doubles, a home run and three RBIs.
  • Vinnie Pasquantino has shown off his power as he paces his team with 31 home runs and 107 runs batted in.
  • Pasquantino is 15th in homers in baseball, and seventh in RBI.
  • Maikel Garcia has 36 doubles, five triples, 16 home runs and 59 walks while hitting .285.
  • Salvador Perez is hitting .240 with 34 doubles, 30 home runs and 25 walks.
  • Perez is riding an eight-game hitting streak into this one. In his last 10 outings he is batting .308 with five home runs, two walks and 15 RBIs.

Royals Team Props

Hits O/UTotal Bases O/UHR O/URBI O/U
Vinnie Pasquantino0.5 (-260)1.5 (+112)––
Salvador Pérez0.5 (-259)1.5 (+101)––
Maikel Garcia0.5 (-263)1.5 (+113)––
Jonathan India0.5 (-204)1.5 (+144)––
Bobby Witt Jr.1.5 (+185)1.5 (-106)––

Angels Recent Betting Performance

  • The Angels have played as underdogs in eight of their past 10 games and lost each of those contests.
  • In their last 10 games with a total, the Angels and their opponents have combined to hit the over six times.
  • The Angels have three wins against the spread in their last 10 chances.

Angels Recent Stats

StatAvg/Total
Record1-9
Runs Per Game2.8
HR16
ERA5.67
K/98.2

Angels Player Insights

  • Ward has driven in the most runs for the Angels with 101 runs batted in.
  • In all of the big leagues, Ward is 10th in homers and 11th in RBI.
  • Ward has collected a hit in five straight games. In his last five games he is batting .421 with three home runs and three RBIs.
  • Jo Adell has shown his power as he leads his team with 36 home runs.
  • Among all MLB hitters, Adell is ninth in homers and 16th in RBI.
  • Nolan Schanuel paces the Angels’ lineup with a .268 batting average.
  • Mike Trout is hitting .229 with 14 doubles, a triple, 22 home runs and 85 walks.

Angels Team Props

Hits O/UTotal Bases O/UHR O/URBI O/U
Jo Adell0.5 (-188)1.5 (+123)––
Oswald Peraza0.5 (-112)–––
Nolan Schanuel0.5 (-174)–––
Mike Trout0.5 (-172)–––
Logan O’Hoppe0.5 (-174)–––

Blue Jays vs. Royals Highlights | MLB on FOX

Blue Jays vs. Royals Highlights | MLB on FOX

Check out the best highlights between the Toronto Blue Jays and Kansas City Royals.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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