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Christina Applegate<\/a>, who was diagnosed with multiple sclerosis<\/a> (MS) in 2021, has reportedly been hospitalized in Los Angeles. TMZ<\/a> reported on April 16 that the actress was admitted to the hospital in late March, and her rep responded to the story with a vague statement.<\/p>\n \u201cI have no comment on whether she is in the hospital or what her medical treatments are,\u201d Applegate\u2019s rep shared. \u201cShe\u2019s had a long history of complicated medical conditions that she has been refreshingly open about, as evidenced in her memoir and on her podcast.\u201d<\/p>\n Applegate hosts the\u00a0MeSsy\u00a0<\/em>podcast with Jamie-Lynn Sigler<\/a>, who went public with her own MS diagnosis in 2016 after being diagnosed when she was 20. The podcast announced a brief hiatus on March 31 due to Applegate and Sigler\u2019s press tours for their books, per TMZ. The Dead to Me<\/a><\/em> star\u00a0released her memoir, You With the Sad Eyes<\/em>, on March 3 and appeared in various interviews promoting the book.<\/p>\n Applegate has been open about the debilitating effects<\/a> of her disease and previously revealed that she\u2019d been hospitalized multiple times while battling symptoms. In her memoir, she admitted that she spends most of her time in bed due to how much pain she is often in.<\/p>\n \u201cWhen I wake up, I often can\u2019t get my arm to move far enough to grab the cup of water by my bed or my phone from its charger,\u201d she wrote in a recent essay for\u00a0The Guardian<\/a>.<\/em> \u201cI have infusions every six months to slow the disease\u2019s progress, but those infusions kill all my B cells [a type of white blood cell that makes antibodies], making me prone to infection. My stomach frequently slows to a halt, leaving me to rush to the emergency room in agony. Most days, simply walking across the room feels like scaling a mountain.\u201d<\/p>\n However, \u201cone of the worst side effects,\u201d she said, is simply the exhaustion. \u201cIt feels as though I\u2019ve been on a three\u2011day sleepless bender \u2013 and that\u2019s how I feel after a good night\u2019s sleep,\u201d Applegate admitted. \u201cHence all the time I spend on and in bed, snuggled up against my heating pad.\u201d<\/p>\n