With the addition of Jane Krakowski, the list of guest stars for Season 2 of Brilliant Minds keeps getting better and better.
The 30 Rock alum joins a growing list of big names that includes Real Housewives of Atlanta starPorsha Williamsand Love on the Spectrum fan favoriteConnor Tomlinson.Molly Bernard and Laura Vandervoort were also announced for Season 2.
Series stars Zachary Quinto,Tamberla Perry, Ashleigh LaThrop, and Alex MacNicholl are among the cast returning for the second season. Brilliant Minds is loosely based on the real-life neurologist, Dr. Oliver Sacks, who died in 2015. His clinical studies and a series of books focused on unusual neurological conditions.
What We Know About Jane Krakowski’s ‘Brilliant Minds’ Appearance
Jane Krakowski will join the Brilliant Minds cast for Season 2, Episode 4, according to Variety. The 30 Rock star is set to play Arianna Burnett, whom they described as “a high-powered businesswoman who fights her conservatorship despite her family’s growing concerns.”
This is the latest role for Krakowski, whose most famous roles, aside from 30 Rock, include Ally McBeal, National Lampoon’s Vacation,and The Flintstones in Viva Rock Vegas.
Krakowski also has a role alongside Arnold Schwarzenegger, Alan Ritchson, and Ken Jeong in The Man With The Bag, which hits theaters in October 2025.
‘Brilliant Minds’ Has a Major Cliffhanger to Address
At the end of Season 1, we found out why Dr. Noah Wolf (Mandy Patinkin) popped up on his son, the brilliant neurologist, Dr. Oliver Wolf (Zachary Quinto), and unfortunately, it was mostly self-serving. The elder Dr. Wolf needed his son to figure out what was going on with him and save his life.
Previously, the show’s main character believed his father was dead, and his mom, who is also the head of the Bronx General Hospital where he works, played along with it. That leaves him feeling betrayed and hurt as he wrestles with this new knowledge about the family.
The father-son dynamic is sure to be an ongoing plot point throughout Season 2 as the medical procedural also deals out a weekly storyline that the brilliant doctor and his team of interns will solve in a timely manner.
Season 2 of Brilliant Minds premieres on NBC on Monday, September 22, 2025, at 10/9c.
Related: 5 Shows You Should Watch Right Now If You Love ‘Brilliant Minds’
This story was originally reported by Parade on Sep 6, 2025, where it first appeared in the News section. Add Parade as a Preferred Source by clicking here.
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