Kansas City Royals vs Oakland Athletics Prediction 9/28/2025 Today’s MLB Picks

In this article, we will formulate a Royals vs Athletics Prediction for this MLB game on Saturday, September 27th at the Sutter Health Park in the second game of this series, with the Athletics having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Athletics Preview

The Athletics have a 76-84 record this season and are sitting on the last place of the AL West. The Athletics have a 36-43 home record and are 77-76 in over/under. They are coming off a 4-3 home win over the Royals, and are 3-1 in their last 4 games. Under is 7-3-1 in their last 11 games.

The Athletics have a .254 batting average this season, .318 OBP and .433 Slugging percentage. Athletics’ pitching staff has a 4.70 ERA and 1.36 WHIP. Brent Rooker leads the Athletics with 164 hits, while Jacob Wilson is the team’s best hitter with a .313 batting average. Tyler Soderstrom adds a team-high 93 RBI, while Nick Kurtz adds a team-high 35 home runs. 

Luis Morales (R) is the projected starter for the Athletics, and he has a 4-2 record, 3.07 ERA and 1.11 WHIP.

Kansas City Royals Preview

The Kansas City Royals have an 80-80 record this season and are sitting on the second place of the AL Central. The Royals have a 37-42 road record and are 70-89 in over/under. They are coming off a 3-4 road defeat by the A’s and over is 7-4 in their last 11 games.

The Royals have a .247 batting average this season, .309 OBP and .396 Slugging percentage. Kansas’ pitching staff has a 3.75 ERA and 1.24 WHIP. Bobby Witt Jr. leads the Royals with 181 hits, and he is the team’s best hitter with a .295 batting average. Vinnie Pasquantino leads the team in RBI, with 111, and a team-high 32 home runs.

Michael Wacha (R) is the projected starter for the Royals, and he has a 9-13 record, 4.00 ERA and 1.24 WHIP.

Kansas City Royals @ Athletics Betting Trends: September 27, 2025

• Probable Starting Pitcher: Luis Morales      Record this season: 4-2      ERA: 3.07
• Home Record: 3-1
• Last 5 against Royals: –

Why the Athletics will win

• The Athletics have won each of their last seven games against AL Central opponents.
• The Royals have lost seven of their last eight night games against the Athletics following a loss.
• The Athletics have covered the run line in each of their last seven games against the Royals.
• The Royals have failed to cover the run line in each of their last six games against the Athletics following a loss.
• The Athletics have led after 3 innings in eight of their last nine Saturday night games as home favorites.
• The Royals have trailed after 5 innings in each of their last four games as underdogs against AL West opponents.

• Probable Starting Pitcher: Michael Wacha      Record this season: 9-13      ERA: 4.00
• Road Record: 4-6
• Last 5 against Athletics: 0-1

Why the Kansas City Royals will win

• The underdogs have won each of the last four games between the Royals and Athletics.
• The Athletics have lost 10 of their last 12 games as home favorites after playing the previous day.
• The Athletics have failed to cover the run line in each of their last six games as home favorites against AL Central opponents.
• The Royals have covered the run line in eight of their last nine games as road underdogs against AL West opponents.
• The Royals have led after 5 innings in seven of their last nine games as road underdogs against AL West opponents.
• The Royals have won the first inning in three of their last four games as road underdogs.
• The Royals have led after 3 innings in six of their last seven games as road underdogs against AL West opponents.

Total Runs Facts

• Each of the Athletics’ last nine games as favorites have gone UNDER the total runs line.
• Four of the Royals’ last five games as underdogs against the Athletics have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Royals’ last six games as road underdogs.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the last six games between the Royals and Athletics.

Athletics Player Prop Facts

• Shea Langeliers has recorded a Double in six of his last seven home appearances against AL Central opponents.
• Shea Langeliers has recorded at least one hit in each of his last 12 appearances against AL Central opponents.
• Zack Gelof has hit a home run in each of his last three appearances against the Royals.
• Jacob Wilson ranks 2nd amongst qualified players for Batting Average (.313) this season.

Kansas City Royals Player Prop Facts

• Salvador Perez has hit at least one home run in each of the Royals’ last two games as road underdogs.
• Michael Wacha has recorded a win in 10 of his last 12 appearances in night games against AL teams that held a losing record.
• Michael Wacha has recorded four or more strikeouts in 19 of his last 22 appearances against AL opponents that held a losing record.
• Jonathan India has recorded at least one hit in each of his 22 previous Saturday night appearances against teams that held a losing record.
• MJ Melendez has recorded at least one Double in three of his last four road appearances against AL West opponents that held a losing record.
• Bobby Witt Jr. ranks T1st in the league in Hits (181) this season.

Matchup/League Facts

• The Athletics rank 2nd in the league for doubles this season (292).
• The Athletics rank 29th in the league for home runs allowed this season (219).
• The Royals rank 2nd in the league for strikeouts against this season (1081).
• The Royals rank 29th in the league for walks this season (426).

Royals vs Athletics Prediction

The Athletics are 6-1 in their last 7 meetings against the Royals, and are 3-1 in their last 4 home meetings. Under is 8-3 in their last 11 meetings.  

In this Royals vs Athletics Prediction, the Athletics are coming as -120 home favorites. Both teams have nothing to play for, and the Royals are putting Wacha on the mound, who has been torched lately, having a 1-4 record and 7.88 ERA across his last 5 starts. On the flip side, Morales has been a good surprise for the A’s this season, who have been playing good baseball to end the season, coming off a series win against the Astros. I like the value with the home team in this one, so take the Athletics on the moneyline in this one.