Angels vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 24

Odds updated as of 8:11 p.m.

The Kansas City Royals are among the MLB teams playing on Wednesday, up against the Los Angeles Angels.

Before checking out the MLB betting lines on FanDuel Sportsbook, we’ve got you covered, in terms of the vital info regarding this matchup.

Kansas City Royals (79-78) vs. Los Angeles Angels (70-87)
Date: Wednesday, September 24, 2025
Time: 9:38 p.m. ET
Venue: Angel Stadium — Anaheim, California
Coverage: FDSW and FDSKC

All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: KC: (-116) | LAA: (-102)
Spread: KC: -1.5 (+142) | LAA: +1.5 (-172)
Total: 8.5 — Over: (-102) | Under: (-120)

Royals vs Angels Probable Starting Pitchers

Probable Pitchers: Stephen Kolek (Royals) – 5-6, 3.54 ERA vs Yusei Kikuchi (Angels) – 6-11, 4.05 ERA

The Royals will look to Stephen Kolek (5-6) versus the Angels and Yusei Kikuchi (6-11). Kolek and his team are 12-6-0 ATS this season when he starts. Kolek’s team has a record of 2-4 this season when he starts and they are the favorite on the moneyline. The Angels are 17-15-0 ATS in Kikuchi’s 32 starts with a set spread. The Angels have a 6-14 record in Kikuchi’s 20 starts this season when they were the underdog on the moneyline.

All MLB win probability predictions and picks are according to numberFire.
Prediction: Royals win (53.2%)

Kansas City is the favorite, -116 on the moneyline, while Los Angeles is a -102 underdog despite being at home.

The Angels are at +1.5 on the runline against the Royals. The Angels are -172 to cover the spread, and the Royals are +142.

A combined run total of 8.5 has been set for Royals-Angels on Sept. 24, with the over at -102 and the under at -120.

Bet on Kansas City Royals vs. Los Angeles Angels on FanDuel today!

The Royals have been victorious in 37, or 57.8%, of the 64 contests they have been chosen as favorites in this season.
This season Kansas City has been victorious 36 times in 63 chances when named as a favorite of at least -116 on the moneyline.
Contests with the Royals have gone over the total set by oddsmakers in 68 of 155 chances this season.
The Royals have an against the spread mark of 76-79-0 in 155 games with a line this season.
The Angels have been the moneyline underdog 116 total times this season. They’ve gone 50-66 in those games.
Los Angeles has a record of 45-60 when playing as a moneyline underdog with odds of -102 or longer (42.9%).
The Angels have played in 155 games with a set over/under, and have combined with their opponents to go over the total 83 times (83-67-5).
The Angels are 81-74-0 ATS this season.

Royals Player Leaders

Bobby Witt Jr. has 176 hits to go with a slugging percentage of .502, both of which are best among Kansas City hitters this season. He has a .293 batting average and an on-base percentage of .351.
Among qualified hitters, he is 11th in batting average, his on-base percentage ranks 36th, and he is 16th in slugging.
Witt hopes to build on a four-game hitting streak in this matchup. During his last five outings he is hitting .304 with two doubles, a home run and four RBIs.
Maikel Garcia leads Kansas City with an OBP of .354 this season while batting .288 with 60 walks and 77 runs scored. He’s slugging .455.
His batting average ranks 16th among qualified players, his on-base percentage 32nd, and his slugging percentage 56th.
Garcia takes a two-game streak with at least one hit into this one. During his last five outings he is hitting .278 with two doubles, three walks and two RBIs.
Vinnie Pasquantino is batting .269 with a .479 slugging percentage and 108 RBI this year.
Salvador Perez has been key for Kansas City with 140 hits, an OBP of .287 plus a slugging percentage of .457.
Perez brings a nine-game hitting streak into this game. In his last 10 outings he is hitting .342 with five home runs, three walks and 16 RBIs.

Angels Player Leaders

Taylor Ward has accumulated a team-best .474 slugging percentage. He’s batting .228 with an on-base percentage of .315.
Including all the qualifying players in the big leagues, his batting average places him 136th, his on-base percentage is 100th, and he is 36th in slugging.
Ward heads into this game on a six-game hitting streak. During his last 10 outings he is hitting .256 with five home runs and five RBIs.
Jo Adell leads his team with 120 hits. He has a batting average of .237 while slugging .488 with an on-base percentage of .296.
His batting average ranks 118th among all qualified players, his on-base percentage ranks 125th, and he is 22nd in slugging.
Nolan Schanuel has put up a team-high .357 on-base percentage.
Mike Trout is hitting .227 with 14 doubles, a triple, 22 home runs and 86 walks.

9/23/2025: 8-4 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -166, Underdog Moneyline: +140)
9/4/2025: 4-3 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -152, Underdog Moneyline: +128)
9/3/2025: 4-3 LAA (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
9/2/2025: 5-1 LAA (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -156, Underdog Moneyline: +132)
8/21/2024: 3-0 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +152)
8/20/2024: 9-5 LAA (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -200, Underdog Moneyline: +168)
8/19/2024: 5-3 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
5/12/2024: 4-2 KC (Favorite: Angels, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
5/11/2024: 9-3 LAA (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -164, Underdog Moneyline: +138)
5/10/2024: 2-1 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)