Angels vs. Royals Prediction, Odds, Picks – September 25

Data Skrive

Taylor Ward and the Los Angeles Angels will play Bobby Witt Jr. and the Kansas City Royals on Thursday at Angel Stadium, at 9:38 p.m. ET. Oddsmakers list the Angels as -110 moneyline favorites, while giving the underdog Royals -110 moneyline odds. Kansas City is favored on the run line (-1.5 with +146 odds). A 9-run over/under is set for this matchup.

Here’s everything you need from a betting perspective on the Angels-Royals game, regarding the run line, moneyline and total, plus expert picks.

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Angels vs. Royals Game Information & Odds

• When: Thursday, September 25, 2025 at 9:38 p.m. ET
• Where: Angel Stadium in Anaheim, California
• How to watch on TV: FDSW and FDSKC

Angels vs. Royals Prediction

• Score Prediction: Royals 5, Angels 4
• Total Prediction: Under 9 runs
• Win Probabilities: Angels 50%, Royals 50%

Angels vs. Royals Betting Insights

• The Angels have entered the game as favorites 39 times this season and won 19, or 48.7%, of those games.
• This season Los Angeles has won 19 of its 39 games, or 48.7%, when favored by at least -110 on the moneyline.
• The oddsmakers’ moneyline implies a 52.4% chance of a victory for the Angels.
• The Royals have come away with 41 wins in the 91 contests they have been listed as the underdogs in this season.
• Kansas City has a win-loss record of 41-50 when favored by -110 or worse by bookmakers this year.
• The Royals have an implied victory probability of 52.4% according to the moneyline set for this matchup.

Angels Recent Betting Performance

• Over the last 10 games, the Angels have been named the moneyline favorite by oddsmakers just two times, and they split those games.
• Over their last 10 outings (all had set totals), the Angels combined with their opponents to hit the over on the total six times.
• The Angels have put together a 2-8-0 record against the spread over their past 10 games.

Angels Recent Stats

Angels Player Insights

• Ward leads the Angels with 102 runs batted in.
• Ward is 10th in homers and 11th in RBI among all hitters in the majors.
• Ward has collected a hit in six games in a row. During his last 10 games he is hitting .256 with five home runs and five RBIs.
• Jo Adell’s 36 home runs lead his team.
• Adell is ninth in homers and 17th in RBI among all major league hitters this year.
• Adell has two games in a row with at least one hit. In his last five games he is batting .222 with two walks and an RBI.
• Nolan Schanuel leads the Angels with a team-high batting average of .268.
• Schanuel has at least one base hit in four games in a row. During his last five outings he is hitting .294 with a double, a home run, two walks and three RBIs.
• Mike Trout is batting .227 with 14 doubles, a triple, 22 home runs and 86 walks.

Royals Recent Betting Performance

• The Royals have played as underdogs in eight of their past 10 games and won three of those contests.
• When it comes to hitting the over, the Royals and their opponents are 8-2-0 in their last 10 games with a total.
• The Royals have five wins against the spread in their last 10 chances.

Royals Recent Stats

Royals Player Insights

• Witt paces the Royals with a .293 batting average.
• Witt is 56th in home runs and 35th in RBI among all hitters in the big leagues.
• Witt has collected a hit in four straight games. In his last five games he is hitting .304 with two doubles, a home run and four RBIs.
• Maikel Garcia is batting .288 with 38 doubles, five triples, 16 home runs and 60 walks.
• Garcia ranks 123rd overall in homers and 77th in RBI this season.
• Vinnie Pasquantino has been solid source of run production for the Royals with 31 long balls and 108 runs batted in.
• Salvador Perez has 34 doubles, 30 home runs and 26 walks while hitting .242.

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