How Seth Rogen had Luke Macfarlane’s back on ‘Platonic’ set

In this studio, Seth Rogen treats his actors with the utmost respect.

Since starring in the Apple TV+ show “Platonic,” Luke Macfarlane has gotten to know the “Knocked Up” star, 43, on a personal level.

In fact, amid Season 2 of the rom-com series, the “Bros” actor, 45, is reflecting on one moment in their friendship that stuck with him.

“Seth really respects what everyone does,” Macfarlane exclusively told The Post. “You know, Seth did an amazing thing once, actually. Somebody on set who kind of shouldn’t have said this, told me to do something.”

He explained, “I was wearing a lav, a microphone, and I brought my hand to my lav, and I covered the lav in the scene. And somebody said something to me like, ‘Oh, don’t do that with your hand, you’ll cover your lav.’”

Rogen, meanwhile, didn’t appreciate the person stepping in.

“And Seth actually said to that person, ‘Don’t tell an actor what to do. That’s not your job,’” Macfarlane reflected. “Just watching somebody look out for his fellow actors – that’s what he does.”

“He’s got integrity,” the Hallmark hunk gushed. “He knows how to look out for his actors. He really cares about an actor feeling comfortable.”

Along with advocating for what’s right, Rogen, of course, kept the laughs coming.

“Seth is very famous for a lot of things. I think he’s really famous for that laugh, you know?” Macfarlane mused. “And I will say, working with Seth, you always want to get him to do that laugh. It makes you very happy when you make Seth laugh. So I will say the most Seth Rogen thing you can get him to do is laugh.”

“Platonic” follows former best friends, Sylvia (Rose Byrne) and Will (Rogen), who reconnect after a years-long rift.

But for Macfarlane’s Charlie, trying to navigate his wife’s reignited friendship isn’t always an easy feat.

Viewers will get a chance to see it all play out this season.

Macfarlane promises these new episodes will encompass “friendship, chaos, and comedy.”

“This second season is different for my character, because in the first season, my character is the rock,” he shared. “This season, he’s definitely the character that is, oof, a little bit sort of lost. Lost in the weeds. So it was fun to kind of explore this other side of him where he’s a little bit more sort of floundering in the universe.”

In real life, though, it’s a whole different story.

Working with Byrne, 46, hits the funny bone — every single time.

“Rose makes me laugh a lot,” Macfarlane dished. “I think we’re filming a scene where I was, like, popping in and out of a doorway, and of course, the timing was hilarious. So we were just making each other laugh because I felt like I kept on missing the entrance.”

“It’s something early in the season where I’m sort of like, you know, doing the sticking my head [in], and I just kept on sticking my head in at the wrong time. So that made us both laugh quite a bit.”

Macfarlane was able to reunite with both of his witty co-stars for the Season 2 red carpet premiere on July 30.

During the event, Byrne dove into the “will-they-won’t-they” of her character’s friendship with Will.

“It’s quite strange to think that this show is quietly groundbreaking because of the subject matter. Because it’s about a very relatable thing, but it’s not discussed, and it’s brought to light in a very fun and funny way,” the actress said, according to The Wrap.

“The show has a very light touch, it’s not heavy, it’s relatable and it’s heartfelt, and it is funny when you think, I don’t know many other shows that are about this – where the core center of the show is this relationship, which is entirely dysfunctional and wonderful.”

Rogen echoed his on-screen bestie’s sentiments, stating: “Traditionally in narrative work, a romantic story is much preferred to a platonic one. I think it is a relatively contemporary idea to even explore friendship, it’s just shedding this old structure of movies and television.”

“Platonic” Season 2 new episodes drop on Apple TV+ every Wednesday.