Jamie-Lynn Sigler to Play Doctor with Ms on ‘Grey’s Anatomy’

After a three-year break from television, The Sopranos actor Jamie-Lynn Sigler is returning to the small screen in an important new guest role on ABC’s Grey’s Anatomy. According to Deadline, Sigler will appear in the January 15, 2026, episode “Heavy on Me,” playing Dr. Laura Kaplan, a urologist living with Multiple Sclerosis. Kaplan is called to Grey Sloan by Dr. Catherine Fox (Debbie Allen) to offer advice to Dr. Richard Webber (James Pickens Jr.), who revealed his cancer diagnosis during the Season 22 mid-season finale. The role was specifically created for Sigler, who has lived with the chronic autoimmune disease for over two decades. She first went public about her battle with…