Kansas City Royals vs Los Angeles Angels Prediction 9/24/2025 Today’s MLB Picks

In this article, we will formulate a Royals vs Angels Prediction for this MLB game on Wednesday, September 24th at the Angel Stadium in the second game of this series, with the Royals having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Los Angeles Angels Preview

The Los Angeles Angels have a 70-87 record this season and are sitting on the 4th place of the AL West. The Angels have a 37-39 home record and 86-68 in over/under They are coming off a 4-8 home defeat by the Royals, and are 1-10 in their last 11 games. They are playing the Astros next.

The Angels have a .226 batting average this season, .299 OBP and .398 Slugging percentage. LA’s pitching staff has a 4.88 ERA and 1.44 WHIP. Taylor Ward leads the Angels with 130 hits, while Nolan Schanuel is the team’s best hitter with a .268 batting average. Taylor Ward leads the team with 102 RBI, while Jo Adell adds a team-high 36 home runs.

Yusei Kikuchi (L) is the projected starting pitcher for the Angels, and he has a 6-11 record, 4.05 ERA and 1.45 WHIP.

Kansas City Royals Preview

The Kansas City Royals have a 79-78 record this season and are sitting on the second place of the AL Central. The Royals have a 36-40 road record and are 69-87 in over/under. They are coming off an 8-4 road victory over the Angels, and are 3-1 in their last 4 games. Over is 8-2 in their last 10 games and are playing the Athletics next.

The Royals have a .248 batting average this season, .309 OBP and .397 Slugging percentage. Kansas’ pitching staff has a 3.76 ERA and 1.25 WHIP. Bobby Witt Jr. leads the Royals with 176 hits, and he is the team’s best hitter with a .293 batting average. Vinnie Pasquantino leads the team in RBI, with 108, and a team-high 31 home runs.

Stephen Kolek (R) is the projected starter for the Royals, and he has a 5-6 record, 3.54 ERA and 1.14 WHIP.

Kansas City Royals @ Los Angeles Angels Betting Trends: September 24, 2025

• Probable Starting Pitcher: Yusei Kikuchi      Record this season: 6-11      ERA: 4.05
• Home Record: 5-3
• Last 5 against Royals: 3-0

Why the Los Angeles Angels will win

• The Royals have lost eight of their last nine games following a road win.
• The home team has won 11 of the Angels’ last 13 games.
• The Angels have covered the run line each of their last seven night games against AL Central opponents that held a winning record.
• The Royals have failed to cover the run line in five of their last six games as underdogs following a road win.
• The Royals have trailed after 5 innings in each of their last four games as underdogs against AL West opponents.
• The Royals have trailed after 3 innings in nine of their last 12 games as road underdogs against American League opponents.

• Probable Starting Pitcher: Stephen Kolek      Record this season: 5-6      ERA: 3.54
• Road Record: 3-2
• Last 5 against Angels: –

Why the Kansas City Royals will win

• The Angels have lost each of their last eight games against teams that held a winning record.
• The underdogs have won five of the Angels’ last seven games at Angel Stadium of Anaheim.
• The Royals have covered the run line in each of their last 10 Wednesday games as road underdogs.
• The Angels have failed to cover the run line in each of their last six games as home favorites.
• The Royals have led after 5 innings in each of their last seven Wednesday night games against opponents that held a losing record.
• The Royals have won the first inning in four of their last five road games.
• The Royals have led after 3 innings in eight of their last nine road games against AL West opponents.

Total Runs Facts

• Seven of the Angels’ last eight night games against American League opponents have gone OVER the total runs line.
• Each of the Royals’ last four road games have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Royals’ last eight road games.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Angels’ last seven games as home favorites against AL Central opponents.

Los Angeles Angels Player Prop Facts

• Yusei Kikuchi has recorded a win in three of his last four appearances against the Royals.
• Jo Adell has hit a home run in four of the Angels’ last five night games against AL Central opponents that held a winning record.
• Yoan Moncada has recorded a Double in three of his last four appearances against the Royals.
• Yusei Kikuchi has recorded five or more strikeouts in 14 of his last 16 appearances with his team as a home favorite against AL opponents.
• Yoan Moncada has recorded a hit in each of his last seven home appearances against the Royals.
• Jo Adell ranks 9th in the league in Home Runs (36) this season.

Kansas City Royals Player Prop Facts

• Salvador Perez has hit at least one home run in each of the Royals’ last two games as road underdogs.
• Vinnie Pasquantino has recorded at least one Double in each of the Royals’ last three road games.
• Vinnie Pasquantino has recorded at least one hit in each of the Royals’ last 10 night games.
• Bobby Witt Jr. ranks 3rd in the league in Hits (176) this season.

Matchup/League Facts

• The Angels rank 30th in the league for doubles this season (207).
• The Angels rank 30th in the league for batting average this season (.226).
• The Royals rank 1st in the league for strikeouts against this season (1056).
• The Royals rank 29th in the league for walks this season (418).

Royals vs Angels Prediction

Both teams are tied 2-2 wins in their last 4 head-to-head meetings, but the Royals are 4-1 in their last 5 visits in Los Angeles. Under is 6-2 in their last 8 meetings.

In this Royals vs Angels Prediction, the Angels are coming as -125 home favorites. The Royals are technically eliminated from the playoffs, and are facing an Angels team with Kikuchi on the mound, who has been significantly better at home, with a 3.00 ERA. But Kolek has also been better on the road, with a 2.31 road ERA, and coming in excellent form, with a 1.91 ERA in his last 5 starts. Kikuchi has been terrible lately, having lost his last 5 starts with an 8.10 ERA, and the Angels have the third-worst bullpen in baseball. Take the Kansas City Royals on the moneyline for plus money in this one.